Cryptogenic gelastic epilepsy of frontal lobe origin: A paediatric case report

Gelastic (laughing) seizures are an uncommon seizure type which in most cases has an organic cerebral pathology and specifically a hypothalamic hamartoma. The interictal EEG frequently shows focal activity. This report describes a 312-year-old boy who presented with episodes of unmotivated laughter...

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Veröffentlicht in:Seizure (London, England) England), 2000-06, Vol.9 (4), p.297-300
Hauptverfasser: Garcı́a, Antonio, Gutiérrez, Marı́a A., Barrasa, Javier, Herranz, José L.
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container_title Seizure (London, England)
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creator Garcı́a, Antonio
Gutiérrez, Marı́a A.
Barrasa, Javier
Herranz, José L.
description Gelastic (laughing) seizures are an uncommon seizure type which in most cases has an organic cerebral pathology and specifically a hypothalamic hamartoma. The interictal EEG frequently shows focal activity. This report describes a 312-year-old boy who presented with episodes of unmotivated laughter associated with other epileptic symptomatology before the age of 3 years. Prolonged ambulatory EEG monitoring recorded electroclinical seizures starting in the right frontal area and spreading to the adjacent frontotemporal region. Neurological examination and brain magnetic resonance imaging were normal. Vigabatrin resulted in immediate remission of the seizures and normalization of the EEG.
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source MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects ambulatory EEG
Anticonvulsants - therapeutic use
child
Child, Preschool
cryptogenic epilepsy
Diagnosis, Differential
Electroencephalography
Epilepsy, Frontal Lobe - diagnosis
Epilepsy, Frontal Lobe - drug therapy
Epilepsy, Frontal Lobe - physiopathology
Epilepsy, Temporal Lobe - diagnosis
Epilepsy, Temporal Lobe - drug therapy
Epilepsy, Temporal Lobe - physiopathology
frontal lobe
gelastic seizure
Humans
Laughter
Magnetic Resonance Imaging
Male
Treatment Outcome
Vigabatrin - therapeutic use
title Cryptogenic gelastic epilepsy of frontal lobe origin: A paediatric case report
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