Cryptogenic gelastic epilepsy of frontal lobe origin: A paediatric case report
Gelastic (laughing) seizures are an uncommon seizure type which in most cases has an organic cerebral pathology and specifically a hypothalamic hamartoma. The interictal EEG frequently shows focal activity. This report describes a 312-year-old boy who presented with episodes of unmotivated laughter...
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Veröffentlicht in: | Seizure (London, England) England), 2000-06, Vol.9 (4), p.297-300 |
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description | Gelastic (laughing) seizures are an uncommon seizure type which in most cases has an organic cerebral pathology and specifically a hypothalamic hamartoma. The interictal EEG frequently shows focal activity. This report describes a 312-year-old boy who presented with episodes of unmotivated laughter associated with other epileptic symptomatology before the age of 3 years. Prolonged ambulatory EEG monitoring recorded electroclinical seizures starting in the right frontal area and spreading to the adjacent frontotemporal region. Neurological examination and brain magnetic resonance imaging were normal. Vigabatrin resulted in immediate remission of the seizures and normalization of the EEG. |
doi_str_mv | 10.1053/seiz.2000.0411 |
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The interictal EEG frequently shows focal activity. This report describes a 312-year-old boy who presented with episodes of unmotivated laughter associated with other epileptic symptomatology before the age of 3 years. Prolonged ambulatory EEG monitoring recorded electroclinical seizures starting in the right frontal area and spreading to the adjacent frontotemporal region. Neurological examination and brain magnetic resonance imaging were normal. Vigabatrin resulted in immediate remission of the seizures and normalization of the EEG.</description><identifier>ISSN: 1059-1311</identifier><identifier>EISSN: 1532-2688</identifier><identifier>DOI: 10.1053/seiz.2000.0411</identifier><identifier>PMID: 10880294</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>ambulatory EEG ; Anticonvulsants - therapeutic use ; child ; Child, Preschool ; cryptogenic epilepsy ; Diagnosis, Differential ; Electroencephalography ; Epilepsy, Frontal Lobe - diagnosis ; Epilepsy, Frontal Lobe - drug therapy ; Epilepsy, Frontal Lobe - physiopathology ; Epilepsy, Temporal Lobe - diagnosis ; Epilepsy, Temporal Lobe - drug therapy ; Epilepsy, Temporal Lobe - physiopathology ; frontal lobe ; gelastic seizure ; Humans ; Laughter ; Magnetic Resonance Imaging ; Male ; Treatment Outcome ; Vigabatrin - therapeutic use</subject><ispartof>Seizure (London, England), 2000-06, Vol.9 (4), p.297-300</ispartof><rights>2000 BEA Trading, Ltd</rights><rights>Copyright 2000 BEA Trading Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c382t-f2a01ec9d687206a90bd8a70a261470ca6001b9f3af83b8abf117d042c83de693</citedby><cites>FETCH-LOGICAL-c382t-f2a01ec9d687206a90bd8a70a261470ca6001b9f3af83b8abf117d042c83de693</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1059131100904114$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10880294$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Garcı́a, Antonio</creatorcontrib><creatorcontrib>Gutiérrez, Marı́a A.</creatorcontrib><creatorcontrib>Barrasa, Javier</creatorcontrib><creatorcontrib>Herranz, José L.</creatorcontrib><title>Cryptogenic gelastic epilepsy of frontal lobe origin: A paediatric case report</title><title>Seizure (London, England)</title><addtitle>Seizure</addtitle><description>Gelastic (laughing) seizures are an uncommon seizure type which in most cases has an organic cerebral pathology and specifically a hypothalamic hamartoma. The interictal EEG frequently shows focal activity. This report describes a 312-year-old boy who presented with episodes of unmotivated laughter associated with other epileptic symptomatology before the age of 3 years. Prolonged ambulatory EEG monitoring recorded electroclinical seizures starting in the right frontal area and spreading to the adjacent frontotemporal region. Neurological examination and brain magnetic resonance imaging were normal. Vigabatrin resulted in immediate remission of the seizures and normalization of the EEG.</description><subject>ambulatory EEG</subject><subject>Anticonvulsants - therapeutic use</subject><subject>child</subject><subject>Child, Preschool</subject><subject>cryptogenic epilepsy</subject><subject>Diagnosis, Differential</subject><subject>Electroencephalography</subject><subject>Epilepsy, Frontal Lobe - diagnosis</subject><subject>Epilepsy, Frontal Lobe - drug therapy</subject><subject>Epilepsy, Frontal Lobe - physiopathology</subject><subject>Epilepsy, Temporal Lobe - diagnosis</subject><subject>Epilepsy, Temporal Lobe - drug therapy</subject><subject>Epilepsy, Temporal Lobe - physiopathology</subject><subject>frontal lobe</subject><subject>gelastic seizure</subject><subject>Humans</subject><subject>Laughter</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Treatment Outcome</subject><subject>Vigabatrin - therapeutic use</subject><issn>1059-1311</issn><issn>1532-2688</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kDtPwzAUhS0EoqWwMqJMbCn32nk4bFXFS6pggdlynJvKKI2DnSKVX0-idGBhumf4zpHux9g1whIhFXeB7M-SA8ASEsQTNsdU8JhnUp4OGdIiRoE4YxchfA5UkaA4ZzMEKYEXyZy9rv2h692WWmuiLTU69EOgzjbUhUPk6qj2ru11EzWupMh5u7XtfbSKOk2V1b0faKMDRZ465_tLdlbrJtDV8S7Yx-PD-_o53rw9vaxXm9gIyfu45hqQTFFlMueQ6QLKSuocNM8wycHoDADLoha6lqKUuqwR8woSbqSoKCvEgt1Ou513X3sKvdrZYKhpdEtuH1SOXIBIR3A5gca7EDzVqvN2p_1BIajRoBoNqtGgGg0OhZvj8r7cUfUHn5QNgJwAGv77tuRVMJZaM-jwZHpVOfvf9i-HzH--</recordid><startdate>20000601</startdate><enddate>20000601</enddate><creator>Garcı́a, Antonio</creator><creator>Gutiérrez, Marı́a A.</creator><creator>Barrasa, Javier</creator><creator>Herranz, José L.</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20000601</creationdate><title>Cryptogenic gelastic epilepsy of frontal lobe origin: A paediatric case report</title><author>Garcı́a, Antonio ; Gutiérrez, Marı́a A. ; Barrasa, Javier ; Herranz, José L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c382t-f2a01ec9d687206a90bd8a70a261470ca6001b9f3af83b8abf117d042c83de693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>ambulatory EEG</topic><topic>Anticonvulsants - therapeutic use</topic><topic>child</topic><topic>Child, Preschool</topic><topic>cryptogenic epilepsy</topic><topic>Diagnosis, Differential</topic><topic>Electroencephalography</topic><topic>Epilepsy, Frontal Lobe - diagnosis</topic><topic>Epilepsy, Frontal Lobe - drug therapy</topic><topic>Epilepsy, Frontal Lobe - physiopathology</topic><topic>Epilepsy, Temporal Lobe - diagnosis</topic><topic>Epilepsy, Temporal Lobe - drug therapy</topic><topic>Epilepsy, Temporal Lobe - physiopathology</topic><topic>frontal lobe</topic><topic>gelastic seizure</topic><topic>Humans</topic><topic>Laughter</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Treatment Outcome</topic><topic>Vigabatrin - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Garcı́a, Antonio</creatorcontrib><creatorcontrib>Gutiérrez, Marı́a A.</creatorcontrib><creatorcontrib>Barrasa, Javier</creatorcontrib><creatorcontrib>Herranz, José L.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Seizure (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Garcı́a, Antonio</au><au>Gutiérrez, Marı́a A.</au><au>Barrasa, Javier</au><au>Herranz, José L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cryptogenic gelastic epilepsy of frontal lobe origin: A paediatric case report</atitle><jtitle>Seizure (London, England)</jtitle><addtitle>Seizure</addtitle><date>2000-06-01</date><risdate>2000</risdate><volume>9</volume><issue>4</issue><spage>297</spage><epage>300</epage><pages>297-300</pages><issn>1059-1311</issn><eissn>1532-2688</eissn><abstract>Gelastic (laughing) seizures are an uncommon seizure type which in most cases has an organic cerebral pathology and specifically a hypothalamic hamartoma. The interictal EEG frequently shows focal activity. This report describes a 312-year-old boy who presented with episodes of unmotivated laughter associated with other epileptic symptomatology before the age of 3 years. Prolonged ambulatory EEG monitoring recorded electroclinical seizures starting in the right frontal area and spreading to the adjacent frontotemporal region. Neurological examination and brain magnetic resonance imaging were normal. Vigabatrin resulted in immediate remission of the seizures and normalization of the EEG.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>10880294</pmid><doi>10.1053/seiz.2000.0411</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | ambulatory EEG Anticonvulsants - therapeutic use child Child, Preschool cryptogenic epilepsy Diagnosis, Differential Electroencephalography Epilepsy, Frontal Lobe - diagnosis Epilepsy, Frontal Lobe - drug therapy Epilepsy, Frontal Lobe - physiopathology Epilepsy, Temporal Lobe - diagnosis Epilepsy, Temporal Lobe - drug therapy Epilepsy, Temporal Lobe - physiopathology frontal lobe gelastic seizure Humans Laughter Magnetic Resonance Imaging Male Treatment Outcome Vigabatrin - therapeutic use |
title | Cryptogenic gelastic epilepsy of frontal lobe origin: A paediatric case report |
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