Regionally Distinct Regulation of Astroglial Neurotransmitter Receptors by Fibroblast Growth Factor-2

Fibroblast growth factor (FGF)-2 is an abundant astroglial cytokine. We have previously shown that FGF-2 downregulates gap junctions in primary astroglial cultures (B. Reuss et al., 1998, Glia 22, 19–30). We demonstrate now that FGF-2 induces astroglial dopamine (DA) sensitivity and D1 dopamine-rece...

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Veröffentlicht in:	Molecular and cellular neuroscience 2000-07, Vol.16 (1), p.42-58
Hauptverfasser:	Reuss, Bernhard, Leung, Doreen S.Y., Ohlemeyer, Carsten, Kettenmann, Helmut, Unsicker, Klaus
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Astrocytes - cytology Astrocytes - drug effects Astrocytes - metabolism Calcium - metabolism Cell Count - drug effects Cells, Cultured Cerebral Cortex - cytology Cerebral Cortex - drug effects Cerebral Cortex - metabolism Corpus Striatum - cytology Corpus Striatum - drug effects Corpus Striatum - metabolism Dopamine - metabolism Dopamine - pharmacology Dopamine Agonists - pharmacology Fibroblast Growth Factor 2 - metabolism Fibroblast Growth Factor 2 - pharmacology Gap Junctions - drug effects Gap Junctions - metabolism Glutamic Acid - metabolism Glutamic Acid - pharmacology Glycyrrhetinic Acid - analogs & derivatives Glycyrrhetinic Acid - pharmacology Intracellular Fluid - drug effects Intracellular Fluid - metabolism Mesencephalon - cytology Mesencephalon - drug effects Mesencephalon - metabolism Octanols - pharmacology Rats Receptors, Dopamine D1 - agonists Receptors, Dopamine D1 - biosynthesis Receptors, Dopamine D1 - genetics Receptors, Neurotransmitter - metabolism RNA, Messenger - biosynthesis
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