A “Traceless” Staudinger Ligation for the Chemoselective Synthesis of Amide Bonds

Here we report a novel modification of our previously reported “Staudinger ligation” that generates an amide bond from an azide and a specifically functionalized phosphine. This method for the selective formation of an amide bond, which does not require the orthogonal protection of distal functional...

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Veröffentlicht in:Organic letters 2000-07, Vol.2 (14), p.2141-2143
Hauptverfasser: Saxon, Eliana, Armstrong, Joshua I, Bertozzi, Carolyn R
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Sprache:eng
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