Receptor-mediated endocytosis of transthyretin by ependymoma cells

Transthyretin (TTR) is involved in the transport of thyroxine (T4) and retinol-binding protein (RBP) in cerebrospinal fluid (CSF) and serum. TTR is secreted in the CSF by the epithelial cells of choroid plexus. The binding of [ 125I]TTR to cultured ependymoma cells which form the brain cerebrospinal...

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Veröffentlicht in:	Brain research 2000-07, Vol.870 (1), p.185-194
Hauptverfasser:	Kuchler-Bopp, Sabine, Dietrich, Jean-Bernard, Zaepfel, Marlyse, Delaunoy, Jean-Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological Transport - physiology Blotting, Northern Brain Neoplasms Cell Line, Transformed - chemistry Cell Line, Transformed - metabolism Cell Line, Transformed - ultrastructure Cell physiology Endocytosis Endocytosis - physiology Ependyma - cytology Ependymal cell Ependymoma ependymoma cells Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Neoplastic Humans Immunocytochemistry Iodine Radioisotopes Mice Mice, Transgenic Microscopy, Electron Molecular and cellular biology Prealbumin - genetics Prealbumin - pharmacokinetics Rats Receptor Receptors, Albumin - analysis Receptors, Albumin - metabolism retinol-binding protein RNA, Messenger - analysis Transthyretin transthyretin receptors
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