Liver and Brain Mucormycosis in a Diabetic Patient Type II Successfully Treated with Liposomial Amphotericin B
A case of liver and brain mucormycosis in a 73-y-old diabetic patient is described. The patient presented with fever and a moderate, tender hepatomegaly and a C/T scan examination of the abdomen and brain showed multiple hepatic and cerebral nodular lesions. The largest of the liver lesions was aspi...
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| Veröffentlicht in: | Scandinavian journal of infectious diseases 2000, Vol.32 (3), p.335-337 |
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| container_title | Scandinavian journal of infectious diseases |
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| creator | George Tsaousis, Anastasia Koutsouri, Charoula Gatsiou, Olga Paniara, Christos Peppas, George Chalevelakis |
| description | A case of liver and brain mucormycosis in a 73-y-old diabetic patient is described. The patient presented with fever and a moderate, tender hepatomegaly and a C/T scan examination of the abdomen and brain showed multiple hepatic and cerebral nodular lesions. The largest of the liver lesions was aspirated and broad hyphae of mucor were demonstrated in the purulent material obtained. The patient was treated successfully (for 40 d) with intravenous liposomal amphotericin B and then with itraconazole for 3 months. To our knowledge, this is the first case of a diabetic patient with both liver and brain mucormycosis who has been treated successfully. |
| doi_str_mv | 10.1080/00365540050166090 |
| format | Article |
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The patient presented with fever and a moderate, tender hepatomegaly and a C/T scan examination of the abdomen and brain showed multiple hepatic and cerebral nodular lesions. The largest of the liver lesions was aspirated and broad hyphae of mucor were demonstrated in the purulent material obtained. The patient was treated successfully (for 40 d) with intravenous liposomal amphotericin B and then with itraconazole for 3 months. To our knowledge, this is the first case of a diabetic patient with both liver and brain mucormycosis who has been treated successfully.</description><identifier>ISSN: 0036-5548</identifier><identifier>EISSN: 1651-1980</identifier><identifier>DOI: 10.1080/00365540050166090</identifier><identifier>PMID: 10879616</identifier><identifier>CODEN: SJIDB7</identifier><language>eng</language><publisher>Basingstoke: Informa UK Ltd</publisher><subject>Aged ; Amphotericin B - therapeutic use ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antifungal agents ; Antifungal Agents - therapeutic use ; Biological and medical sciences ; Brain Diseases - diagnosis ; Brain Diseases - drug therapy ; Brain Diseases - microbiology ; Diabetes Mellitus, Type 2 - complications ; Female ; Humans ; Liver Diseases - diagnosis ; Liver Diseases - drug therapy ; Liver Diseases - microbiology ; Medical sciences ; Mucormycosis - complications ; Mucormycosis - diagnosis ; Mucormycosis - drug therapy ; Opportunistic Infections - complications ; Opportunistic Infections - diagnosis ; Opportunistic Infections - drug therapy ; Pharmacology. 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The patient presented with fever and a moderate, tender hepatomegaly and a C/T scan examination of the abdomen and brain showed multiple hepatic and cerebral nodular lesions. The largest of the liver lesions was aspirated and broad hyphae of mucor were demonstrated in the purulent material obtained. The patient was treated successfully (for 40 d) with intravenous liposomal amphotericin B and then with itraconazole for 3 months. To our knowledge, this is the first case of a diabetic patient with both liver and brain mucormycosis who has been treated successfully.</description><subject>Aged</subject><subject>Amphotericin B - therapeutic use</subject><subject>Antibiotics. Antiinfectious agents. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antifungal agents</topic><topic>Antifungal Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Brain Diseases - diagnosis</topic><topic>Brain Diseases - drug therapy</topic><topic>Brain Diseases - microbiology</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Female</topic><topic>Humans</topic><topic>Liver Diseases - diagnosis</topic><topic>Liver Diseases - drug therapy</topic><topic>Liver Diseases - microbiology</topic><topic>Medical sciences</topic><topic>Mucormycosis - complications</topic><topic>Mucormycosis - diagnosis</topic><topic>Mucormycosis - drug therapy</topic><topic>Opportunistic Infections - complications</topic><topic>Opportunistic Infections - diagnosis</topic><topic>Opportunistic Infections - drug therapy</topic><topic>Pharmacology. 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| ispartof | Scandinavian journal of infectious diseases, 2000, Vol.32 (3), p.335-337 |
| issn | 0036-5548 1651-1980 |
| language | eng |
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| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Access via Taylor & Francis |
| subjects | Aged Amphotericin B - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antifungal Agents - therapeutic use Biological and medical sciences Brain Diseases - diagnosis Brain Diseases - drug therapy Brain Diseases - microbiology Diabetes Mellitus, Type 2 - complications Female Humans Liver Diseases - diagnosis Liver Diseases - drug therapy Liver Diseases - microbiology Medical sciences Mucormycosis - complications Mucormycosis - diagnosis Mucormycosis - drug therapy Opportunistic Infections - complications Opportunistic Infections - diagnosis Opportunistic Infections - drug therapy Pharmacology. Drug treatments |
| title | Liver and Brain Mucormycosis in a Diabetic Patient Type II Successfully Treated with Liposomial Amphotericin B |
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