Human chromaffin cell graft into the CSF for cancer pain management: a prospective phase II clinical study

A number of pre-clinical studies have demonstrated the value of adrenal medullary allografts in the management of chronic pain. The present longitudinal survey studied 15 patients transplanted for intractable cancer pain after failure of systemic opioids due to the persistence of undesirable side-ef...

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Veröffentlicht in:	Pain (Amsterdam) 2000-07, Vol.87 (1), p.19-32
Hauptverfasser:	Lazorthes, Yves, Sagen, Jacqueline, Sallerin, Brigitte, Tkaczuk, Jean, Duplan, Hélène, Sol, Jean-Christophe, Tafani, Mathieu, Bès, Jean-Claude
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Allograft Analgesics, Opioid - administration & dosage Biological and medical sciences Cancer pain Cerebrospinal fluid. Spinal cord. Spinal roots. Spinal nerves Chromaffin cell Chromaffin Cells - transplantation Enkephalin, Methionine - cerebrospinal fluid Feasibility Studies Female Humans Injections, Spinal Intrathecal morphine Male Medical sciences Met-enkephalin Middle Aged Morphine - administration & dosage Neoplasms - complications Neurosurgery Pain - cerebrospinal fluid Pain - drug therapy Pain - etiology Pain - surgery Pain Measurement Pilot Projects Prospective Studies Severity of Illness Index Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Transplantation, Homologous Treatment Outcome
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