Glial cell survival is enhanced during melatonin‐induced neuroprotection against cerebral ischemia

The role of glial cells in neuronal death has become a major research interest. Glial cell activation has been demonstrated to accompany cerebral ischemia. However, there is disagreement whether such gliosis is a cell death or a neuroprotective response. In the present study, we examined alterations...

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Veröffentlicht in:	The FASEB journal 2000-07, Vol.14 (10), p.1307-1317
Hauptverfasser:	Borlongan, Cesario V., Yamamoto, Mitsuharu, Takei, Norie, Kumazaki, Michiko, Ungsuparkorn, Chutcharin, Hida, Hideki, Sanberg, Paul R., Nishino, Hitoo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals astrocytes Brain Ischemia - pathology Brain Ischemia - physiopathology Brain Ischemia - prevention & control cell death Cell Death - drug effects Cell Survival - drug effects Cerebral Infarction - pathology Cerebral Infarction - prevention & control Free Radical Scavengers - pharmacology free radicals gliosis Gliosis - pathology Gliosis - prevention & control In Vitro Techniques Male Melatonin - pharmacology Motor Skills - drug effects Neuroglia - cytology Neuroglia - drug effects Neurons - drug effects Neurons - pathology Neuroprotective Agents - pharmacology Rats Rats, Wistar Reperfusion Injury - pathology Reperfusion Injury - prevention & control stroke
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