The adaptable lin-39

Comparative studies of nematode development provide a powerful framework for investigating the evolution of developmental mechanisms. A recent report also demonstrates how comparative work can inform our understanding of basic developmental signaling pathways. In particular, investigation of the dif...

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Veröffentlicht in:Nature genetics 2001-10, Vol.29 (2), p.106-107
1. Verfasser: Chamberlin, Helen M.
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description Comparative studies of nematode development provide a powerful framework for investigating the evolution of developmental mechanisms. A recent report also demonstrates how comparative work can inform our understanding of basic developmental signaling pathways. In particular, investigation of the differences in vulva development between Caenorhabditis elegans and Pristionchus pacificus has clarified the molecular relationship between an epidermal growth factor–Ras–MAP kinase signaling pathway and downstream Hox transcription factor activity.
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subjects Agriculture
Animal Genetics and Genomics
Animals
Biological Evolution
Biomedical and Life Sciences
Biomedicine
Caenorhabditis elegans
Caenorhabditis elegans - genetics
Caenorhabditis elegans Proteins
Cancer Research
Comparative studies
Female
Gene expression
Gene Function
Genetic aspects
Homeodomain Proteins - genetics
Homeodomain Proteins - metabolism
Human Genetics
Mitogen-Activated Protein Kinases - metabolism
news-and-views
Nucleotide sequence
Physiological aspects
ras Proteins - metabolism
Receptor, Epidermal Growth Factor - metabolism
Signal Transduction
Vulva - growth & development
title The adaptable lin-39
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