Characterization of the Role of Medial Prefrontal Cortex Dopamine Receptors in Cocaine-Induced Locomotor Activity

Medial prefrontal cortex (mPFC) dopamine (DA) modulates the motor-stimulant response to cocaine. The present study examined the specific mPFC DA receptor subtypes that mediate this behavioral response. Intra-mPFC injection of the DA D 2 -like receptor agonist quinpirole blocked cocaine-induced motor...

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Veröffentlicht in:	Behavioral neuroscience 2001-10, Vol.115 (5), p.1093-1100
Hauptverfasser:	Beyer, C. E, Steketee, J. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictive behaviors Adult and adolescent clinical studies Animal Animal Locomotion Animals Biological and medical sciences Brain Mapping Cocaine Cocaine - pharmacology Dopamine Drug addiction Injections Male Medial Prefrontal Cortex Medical sciences Motor ability Motor Activity - drug effects Neural Receptors Neurology Neurotransmitters Prefrontal Cortex Prefrontal Cortex - drug effects Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry quinpirole Rats Rats, Sprague-Dawley Receptors, Dopamine D2 - drug effects
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