Polycitone B and Prepolycitrin A: Two Novel Alkaloids from the Marine Ascidian Polycitor africanus
Two novel compounds, polycitone B (4) and prepolycitrin A (3), were isolated from the marine ascidian Polycitor africanus. The structures of these new dibromotyrosine metabolites were established mainly on the basis of NMR spectroscopic data. Isolation of compound 3 supports the earlier suggestion t...
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Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 2000-06, Vol.63 (6), p.832-833 |
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creator | Rudi, Amira Evan, Tamar Aknin, Maurice Kashman, Yoel |
description | Two novel compounds, polycitone B (4) and prepolycitrin A (3), were isolated from the marine ascidian Polycitor africanus. The structures of these new dibromotyrosine metabolites were established mainly on the basis of NMR spectroscopic data. Isolation of compound 3 supports the earlier suggestion that it is the bioprecursor of polycitrin A (2). |
doi_str_mv | 10.1021/np9905158 |
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Nat. Prod</addtitle><description>Two novel compounds, polycitone B (4) and prepolycitrin A (3), were isolated from the marine ascidian Polycitor africanus. The structures of these new dibromotyrosine metabolites were established mainly on the basis of NMR spectroscopic data. Isolation of compound 3 supports the earlier suggestion that it is the bioprecursor of polycitrin A (2).</description><subject>alkaloids</subject><subject>Alkaloids - chemistry</subject><subject>Alkaloids - isolation & purification</subject><subject>Animals</subject><subject>Ascidiacea</subject><subject>Biological and medical sciences</subject><subject>Furans - chemistry</subject><subject>Furans - isolation & purification</subject><subject>General pharmacology</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Marine</subject><subject>Medical sciences</subject><subject>Models, Chemical</subject><subject>natural products</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Polycitone B</subject><subject>Polycitor africanus</subject><subject>Prepolycitrin A</subject><subject>Pyrroles - chemistry</subject><subject>Pyrroles - isolation & purification</subject><subject>Urochordata - chemistry</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0E9PFDEYBvCGaGBFDn4B04OaeBjs2-mfqbeVKJqALGE5N91OJxZm27WdUbl59WvySSiZFT2YeGje5H1_edI8CD0DcgiEwpuwUYpw4M0OmgGnpBKE8kdoRkDUVd0Itoee5HxFCKmJ4rtoD0gjFAU6Q24R-xvrhxgcfodNaPEiuc20Sz7g-dvbn7_w8nvEn-M31-N5f2366NuMuxTXePji8Kkp0OF5tr71JuDfiQmbLnlrwpifosed6bM72M59dPnh_fLoY3VydvzpaH5SGSb5UAkJzrZMcLC8W6nWdXYFZVGesopZCeXGLFsRBlwR2nAiGkIlA2Fs40y9j15NuZsUv44uD3rts3V9b4KLY9YSKDAG8r8QpBQCVFPg6wnaFHNOrtOb5Ncm3Wgg-r58_VB-sc-3oeNq7dq_5NR2AS-2wGRr-i6ZYH3-4xgVjbjPqSbm8-B-PJxNutZC1pLr5eJCF3t8QeuFPi_-5eSNzfoqjimUjv_xvzukQ6aW</recordid><startdate>20000601</startdate><enddate>20000601</enddate><creator>Rudi, Amira</creator><creator>Evan, Tamar</creator><creator>Aknin, Maurice</creator><creator>Kashman, Yoel</creator><general>American Chemical Society</general><general>American Society of Pharmacognosy</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>F1W</scope><scope>FR3</scope><scope>H95</scope><scope>H99</scope><scope>L.F</scope><scope>L.G</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20000601</creationdate><title>Polycitone B and Prepolycitrin A: Two Novel Alkaloids from the Marine Ascidian Polycitor africanus</title><author>Rudi, Amira ; Evan, Tamar ; Aknin, Maurice ; Kashman, Yoel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a475t-671ecd4651c5fb9defcb1cd41cd9c94c714654c4b041590285068027416ac8ea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>alkaloids</topic><topic>Alkaloids - chemistry</topic><topic>Alkaloids - isolation & purification</topic><topic>Animals</topic><topic>Ascidiacea</topic><topic>Biological and medical sciences</topic><topic>Furans - chemistry</topic><topic>Furans - isolation & purification</topic><topic>General pharmacology</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Marine</topic><topic>Medical sciences</topic><topic>Models, Chemical</topic><topic>natural products</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Polycitone B</topic><topic>Polycitor africanus</topic><topic>Prepolycitrin A</topic><topic>Pyrroles - chemistry</topic><topic>Pyrroles - isolation & purification</topic><topic>Urochordata - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rudi, Amira</creatorcontrib><creatorcontrib>Evan, Tamar</creatorcontrib><creatorcontrib>Aknin, Maurice</creatorcontrib><creatorcontrib>Kashman, Yoel</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>ASFA: Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rudi, Amira</au><au>Evan, Tamar</au><au>Aknin, Maurice</au><au>Kashman, Yoel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polycitone B and Prepolycitrin A: Two Novel Alkaloids from the Marine Ascidian Polycitor africanus</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. Nat. Prod</addtitle><date>2000-06-01</date><risdate>2000</risdate><volume>63</volume><issue>6</issue><spage>832</spage><epage>833</epage><pages>832-833</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><coden>JNPRDF</coden><abstract>Two novel compounds, polycitone B (4) and prepolycitrin A (3), were isolated from the marine ascidian Polycitor africanus. The structures of these new dibromotyrosine metabolites were established mainly on the basis of NMR spectroscopic data. Isolation of compound 3 supports the earlier suggestion that it is the bioprecursor of polycitrin A (2).</abstract><cop>Washington, DC</cop><cop>Glendale, AZ</cop><pub>American Chemical Society</pub><pmid>10869212</pmid><doi>10.1021/np9905158</doi><tpages>2</tpages></addata></record> |
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subjects | alkaloids Alkaloids - chemistry Alkaloids - isolation & purification Animals Ascidiacea Biological and medical sciences Furans - chemistry Furans - isolation & purification General pharmacology Magnetic Resonance Spectroscopy Marine Medical sciences Models, Chemical natural products Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Polycitone B Polycitor africanus Prepolycitrin A Pyrroles - chemistry Pyrroles - isolation & purification Urochordata - chemistry |
title | Polycitone B and Prepolycitrin A: Two Novel Alkaloids from the Marine Ascidian Polycitor africanus |
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