Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior

Insulin secretion from glucose-stimulated pancreatic beta-cells is oscillatory, and this is thought to result from oscillations in glucose metabolism. One of the primary metabolic stimulus-secretion coupling factors is the ATP/ADP ratio, which can oscillate as a result of oscillations in glycolysis....

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Veröffentlicht in:	The Journal of biological chemistry 2001-10, Vol.276 (40), p.36946-36950
Hauptverfasser:	Deeney, J T, Köhler, M, Kubik, K, Brown, G, Schultz, V, Tornheim, K, Corkey, B E, Berggren, P O
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - metabolism Adenosine Triphosphate - metabolism Animals Calcium - metabolism Cricetinae Glucose - pharmacology Insulin - metabolism Islets of Langerhans - drug effects Islets of Langerhans - metabolism Tumor Cells, Cultured
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