Intrascleral Concentration vs Depth Profile of Mitomycin-C after Episcleral Application: Impact of Applied Concentration and Volume of Mitomycin-C Solution

The purpose of this study was to investigate the impact of different concentrations and volumes of Mitomycin-C (MMC) on the intrascleral concentration vs depth profile of MMC in an experimental model. The episcleral sides of scleral quadrants of human donor eyes were exposed for 1min to sponges (cor...

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Veröffentlicht in:	Experimental eye research 2000-05, Vol.70 (5), p.571-575
Hauptverfasser:	Vass, C, Georgopoulos, M, El Menyawi, I, Radda, S, Nimmerrichter, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Administration, Topical Biological and medical sciences Chromatography, High Pressure Liquid ciliary body complication concentration Dose-Response Relationship, Drug Eye filtering surgery Glaucoma Glaucoma - metabolism Glaucoma - surgery Humans Medical sciences Mitomycin - pharmacokinetics mitomycin-C Nucleic Acid Synthesis Inhibitors - pharmacokinetics Pharmacology. Drug treatments Sclera - drug effects Sclera - metabolism toxicity Trabeculectomy
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