Glucose Deprivation-Induced Oxidative Stress in Human Tumor Cells: A Fundamental Defect in Metabolism?

: Recently, glucose deprivation‐induced oxidative stress has been shown to cause cytotoxicity, activation of signal transduction (i.e., ERK1, ERK2, JNK, and Lyn kinase), and increased expression of genes associated with malignancy (i.e., bFGF and c‐Myc) in MCF‐7/ADR human breast cancer cells. These...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2000-01, Vol.899 (1), p.349-362
Hauptverfasser:	SPITZ, DOUGLAS R., SIM, JULIA E., RIDNOUR, LISA A., GALOFORO, SANDRA S., LEE, YONG J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Glucose - deficiency Humans Oxidative Stress Tumor Cells, Cultured
Online-Zugang:	Volltext
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