Iduronic Acid-Containing Glycosaminoglycans on Target Cells Are Required for Efficient Respiratory Syncytial Virus Infection

Respiratory syncytial virus (RSV) is an important human respiratory pathogen, particularly in infants. Glycosaminoglycans (GAGs) have been implicated in the initiation of RSV infection of cultured cells, but it is not clear what type of GAGs and GAG components are involved, whether the important GAG...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2000-06, Vol.271 (2), p.264-275
Hauptverfasser:	Hallak, Louay K., Collins, Peter L., Knudson, Warren, Peeples, Mark E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CHO Cells Chondroitin Lyases Chondroitin Sulfates - physiology Cricetinae glycosaminoglycans Glycosaminoglycans - metabolism Green Fluorescent Proteins Heparin - metabolism Heparin Lyase Heparitin Sulfate - metabolism Heparitin Sulfate - physiology Human respiratory syncytial virus Humans iduronic acid Iduronic Acid - metabolism Luminescent Proteins - genetics Polysaccharide-Lyases Protamines - metabolism Receptors, Virus - metabolism Respiratory Syncytial Virus, Human - genetics Respiratory Syncytial Virus, Human - metabolism Respiratory Syncytial Virus, Human - physiology Solubility Tumor Cells, Cultured
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