Valproic Acid Is Effective in Migraine Prophylaxis at Low Serum Levels: A Prospective Open-Label Study

Objective.—We evaluated the efficacy of prophylactic valproic acid treatment (6 months) on the frequency of migraine attacks and the number of migraine headache days with respect to serum levels. Background.—Valproic acid, a GABAergic drug, has been shown to be effective for migraine prophylaxis. Re...

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Veröffentlicht in:	Headache 2001-09, Vol.41 (8), p.774-778
Hauptverfasser:	Kinze, Stephan, Clauss, Michael, Reuter, Uwe, Wolf, Tilo, Dreier, Jens Peter, Einhäupl, Karl Max, Arnold, Guy
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - administration & dosage Anticonvulsants - blood Anticonvulsants - therapeutic use Biological and medical sciences Cardiovascular system Dose-Response Relationship, Drug Female headache Humans Male Medical sciences Middle Aged Migraine Disorders - prevention & control migraine prophylaxis Pharmacology. Drug treatments Prospective Studies treatment valproate Valproic Acid - administration & dosage Valproic Acid - blood Valproic Acid - therapeutic use Vasodilator agents. Cerebral vasodilators
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