Extrastriatal Mean Regional Uptake of Fluorine-18-FDOPA in the Normal Aged Brain—An Approach Using MRI-Aided Spatial Normalization

The aim of this study was to define the mean regional 6-[18F]fluoro-l-dopa (FDOPA) uptake rate constant (Ki) values in the striatal and extrastriatal regions of the brain of normal subjects using magnetic resonance imaging (MRI)-aided spatial normalization of the FDOPA Ki image and using automatic r...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2000-06, Vol.11 (6), p.760-766
Hauptverfasser:	Nagano, Atsuko S., Ito, Kengo, Kato, Takashi, Arahata, Yutaka, Kachi, Teruhiko, Hatano, Kentaro, Kawasumi, Yasuhiro, Nakamura, Akinori, Yamada, Takako, Abe, Yuji, Ishigaki, Takeo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging - metabolism Amygdala Brain - metabolism Caudate nucleus Dihydroxyphenylalanine Dihydroxyphenylalanine - analogs & derivatives Dihydroxyphenylalanine - pharmacokinetics Dopamine receptors Female Fluorine Radioisotopes - pharmacokinetics Humans Image processing Levodopa Magnetic Resonance Imaging Male Mesencephalon Middle Aged Neostriatum Neuroimaging NMR Nuclear magnetic resonance Positron emission tomography Prefrontal cortex Putamen Reference Values Tissue Distribution Visual Cortex - metabolism
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