Peroxidases Inhibit Nitric Oxide (NO) Dependent Bronchodilation: Development of a Model Describing NO−Peroxidase Interactions

Recent studies demonstrate that nitric oxide (NO) serves as a physiological substrate for mammalian peroxidases [(2000) J. Biol. Chem. 275, 37524]. We now show that eosinophil peroxidase (EPO) and lactoperoxidase (LPO), peroxidases known to be enriched in airways of asthmatic subjects, function as a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Easton) 2001-10, Vol.40 (39), p.11866-11875
Hauptverfasser:	Abu-Soud, Husam M, Khassawneh, Mohamed Y, Sohn, Ju-Tae, Murray, Paul, Haxhiu, Musia A, Hazen, Stanley L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma - enzymology Asthma - physiopathology Bronchi - enzymology Bronchi - metabolism Bronchi - physiology Catalysis Humans In Vitro Techniques Kinetics Muscle Relaxation - physiology Nitric Oxide - antagonists & inhibitors Nitric Oxide - metabolism Nitric Oxide - physiology Peroxidases - metabolism Swine Trachea - enzymology Trachea - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!