Members of the Ikaros Gene Family Are Present in Early Representative Vertebrates

Members of the Ikaros multigene family of zinc finger proteins are expressed in a tissue-specific manner and most are critical determinants in the development of both the B and T lymphocytes as well as NK and dendritic APC lineages. A PCR amplification strategy that is based on regions of shared seq...

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Veröffentlicht in:	The Journal of immunology (1950) 2000-07, Vol.165 (1), p.306-312
Hauptverfasser:	Haire, Robert N, Miracle, Ann L, Rast, Jonathan P, Litman, Gary W
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Chickens DNA-Binding Proteins Gene Amplification Gene Expression - immunology Humans Ikaros gene Ikaros Transcription Factor Lampreys - genetics Lampreys - immunology Mammalia Marine Mice Molecular Sequence Data Multigene Family - immunology Organ Specificity - genetics Organ Specificity - immunology Petromyzon marinus Phylogeny Raja eglanteria Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Skates (Fish) - genetics Skates (Fish) - immunology Transcription Factors - genetics Trout Vertebrata Zebrafish Zebrafish Proteins Zinc Fingers - genetics Zinc Fingers - immunology
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