Effects of weekly administration of pegylated recombinant human OB protein on appetite profile and energy metabolism in obese men

Results of leptin administration in mice, rats, and humans provide a rationale for therapeutic augmentation of circulating leptin (OB protein) concentrations in obese humans; this may reduce food intake, increase metabolic rate, and lower body mass. We assessed the effects of weekly subcutaneous peg...

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Veröffentlicht in:	The American journal of clinical nutrition 2001-10, Vol.74 (4), p.426-434
Hauptverfasser:	WESTERTERP-PLANTENGA, Margriet S, SARIS, Wim H. M, HUKSHORN, Chris J, CAMPFIELD, L. Arthur
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Appetite - drug effects Biological and medical sciences Body Mass Index Diet Double-Blind Method Eating - drug effects Energy Metabolism - drug effects Hormones. Endocrine system Humans Leptin - pharmacology Male Medical sciences Men Metabolism Middle Aged Nutrition Obesity Obesity - metabolism Pharmacology. Drug treatments Proteins
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