EXO1 and MSH4 differentially affect crossing-over and segregation

The 5'-3' exonuclease Exo1p from Saccharomyces cerevisiae is required for wild-type levels of meiotic crossing-over and normal meiotic chromosome segregation as is the meiosis-specific MutS homologue, Msh4p. Mutations in both genes reduce crossing-over by approximately two-fold, but deltam...

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Veröffentlicht in:	Chromosoma 2000, Vol.109 (1/2), p.94-102
Hauptverfasser:	Khazanehdari, K.A, Borts, R.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Chromosome Segregation - genetics Crossing Over, Genetic - genetics DNA-Binding Proteins EXO1 gene exo1 protein Exodeoxyribonucleases - genetics Exodeoxyribonucleases - metabolism Fungal Proteins - genetics Gene Deletion Genetic Markers Meiosis - genetics MSH4 gene plant breeding plant genetics Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Spores, Fungal - genetics
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