Mechanisms of programmed cell death in the developing brain

Programmed cell death (apoptosis) is an important mechanism that determines the size and shape of the vertebrate nervous system. Recent gene-targeting studies have indicated that homologs of the cell-death pathway in the nematode Caenorhabditis elegans have analogous functions in apoptosis in the de...

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Veröffentlicht in:	Trends in Neurosciences 2000-07, Vol.23 (7), p.291-297
Hauptverfasser:	Kuan, Chia-Yi, Roth, Kevin A., Flavell, Richard A., Rakic, Pasko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - physiology Biological and medical sciences Brain Brain - embryology Brain - growth & development Caenorhabditis elegans Caenorhabditis elegans Proteins Caspases - physiology Cell Death - physiology Cells Cysteine Endopeptidases - physiology Fundamental and applied biological sciences. Psychology General aspects. Models. Methods Mammalia Neurology Proto-Oncogene Proteins c-bcl-2 - physiology Vertebrates: nervous system and sense organs Worms
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