Quantitative conformational analysis of the core region of N-glycans using residual dipolar couplings, aqueous molecular dynamics, and steric alignment

A method is described for quantitatively investigating the dynamic conformation of small oligosaccharides containing an alpha(1 --> 6) linkage. It was applied to the oligosaccharide Man-alpha(1 --> 3) [Man-alpha(1 --> 6)] Man-alpha-O-Me, which is a core region frequently observed in N-linke...

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Veröffentlicht in:	Journal of biomolecular NMR 2001-08, Vol.20 (4), p.351-363
Hauptverfasser:	Almond, A, Duus, J O
Format:	Artikel
Sprache:	eng
Schlagworte:	Aqueous solutions Carbohydrate Conformation Computer Simulation Crystallography Magnetic Resonance Spectroscopy Mathematics Molecular Conformation Molecular Structure Polysaccharides - chemistry Polysaccharides - metabolism Studies Water - chemistry
Online-Zugang:	Volltext
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