Positron emission tomography shows that impaired frontal lobe functioning in Parkinson’s disease is related to dopaminergic hypofunction in the caudate nucleus

We examined the relation between the dopaminergic function and the cognitive performance of patients with Parkinson's disease (PD). The subject sample consisted of ten patients in the early course of PD and with no previous antiparkinsonian medication. The dopaminergic function of the caudate n...

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Veröffentlicht in:	Neuroscience letters 2001-09, Vol.311 (2), p.81-84
Hauptverfasser:	Brück, Anna, Portin, Raija, Lindell, Arja, Laihinen, Arto, Bergman, Jörgen, Haaparanta, Merja, Solin, Olof, Rinne, Juha O
Format:	Artikel
Sprache:	eng
Schlagworte:	[ 18F]fluorodopa Adult Biological and medical sciences Caudate nucleus Caudate Nucleus - physiopathology Cognition Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dihydroxyphenylalanine - analogs & derivatives Dopamine - physiology Female Fluorine Radioisotopes Frontal Lobe - physiopathology Frontal lobe functions Humans Male Medical sciences Middle Aged Neurology Parkinson Disease - diagnostic imaging Parkinson Disease - physiopathology Parkinson's disease Positron emission tomography The Stroop test Tomography, Emission-Computed
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