A weighted average likelihood ratio test for spatial clustering of disease
We consider methods proposed for detecting localized spatial clustering. We propose a new test statistic, the weighted average likelihood ratio test, as an alternative to the spatial scan (maximum likelihood ratio) test statistic. Two different types of weights are considered. We propose an unbiased...
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| Veröffentlicht in: | Statistics in medicine 2001-10, Vol.20 (19), p.2977-2987 |
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| container_title | Statistics in medicine |
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| creator | Gangnon, Ronald E. Clayton, Murray K. |
| description | We consider methods proposed for detecting localized spatial clustering. We propose a new test statistic, the weighted average likelihood ratio test, as an alternative to the spatial scan (maximum likelihood ratio) test statistic. Two different types of weights are considered. We propose an unbiased cluster selection criterion and evaluate the bias of the tests through simulation. We also examine the power of the tests through simulations and apply the methods to the well‐known New York leukaemia data. Copyright © 2001 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/sim.917 |
| format | Article |
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Copyright © 2001 John Wiley & Sons, Ltd.</description><subject>Biological and medical sciences</subject><subject>Cluster Analysis</subject><subject>Computerized, statistical medical data processing and models in biomedicine</subject><subject>Epidemiologic Methods</subject><subject>Humans</subject><subject>Leukemia - epidemiology</subject><subject>Likelihood Functions</subject><subject>Medical sciences</subject><subject>Medical statistics</subject><subject>New York - epidemiology</subject><issn>0277-6715</issn><issn>1097-0258</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10E1P4zAQBmALLVoKrPgHyJddDihgx7GdHAEtBQTsAVZwsybOpBjcptgp0H-PUSo4cRqN9Gg-XkJ2ODvgjOWH0U0PKq7XyIizSmcsl-UPMmK51pnSXG6QzRgfGeNc5von2UhVlZUUI3JxRF_RTR56bCi8YIAJUu-e0LuHrmtogN51tMfY07YLNM5TD55av4g9Bjeb0K6ljYsIEbfJegs-4q9V3SL_T__enpxll__G5ydHl5ktinSPkHXFBCBvVM2lqBFLgNKqwrJaa9SQN6xSsgRVqqJqhNZtjlLVzBZ5yyohtsifYe48dM-LdJqZumjRe5hht4hGc16m9_IE9wZoQxdjwNbMg5tCWBrOzEdsJsVmUmxJ7q5GLuopNl9ulVMCv1cAogXfBphZF79cwSqpizK5_cG9Oo_L7_aZm_OrYW02aJfSfPvUEJ6M0kJLc3c9Njf3t-mh4wtzLN4BXDORkA</recordid><startdate>20011015</startdate><enddate>20011015</enddate><creator>Gangnon, Ronald E.</creator><creator>Clayton, Murray K.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20011015</creationdate><title>A weighted average likelihood ratio test for spatial clustering of disease</title><author>Gangnon, Ronald E. ; Clayton, Murray K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4477-35b903ae1d6b153bee8aa8c64c0b77e7a2d09658a68649d377f2e56b0c42f0933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Biological and medical sciences</topic><topic>Cluster Analysis</topic><topic>Computerized, statistical medical data processing and models in biomedicine</topic><topic>Epidemiologic Methods</topic><topic>Humans</topic><topic>Leukemia - epidemiology</topic><topic>Likelihood Functions</topic><topic>Medical sciences</topic><topic>Medical statistics</topic><topic>New York - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gangnon, Ronald E.</creatorcontrib><creatorcontrib>Clayton, Murray K.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Statistics in medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gangnon, Ronald E.</au><au>Clayton, Murray K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A weighted average likelihood ratio test for spatial clustering of disease</atitle><jtitle>Statistics in medicine</jtitle><addtitle>Statist. 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| ispartof | Statistics in medicine, 2001-10, Vol.20 (19), p.2977-2987 |
| issn | 0277-6715 1097-0258 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Biological and medical sciences Cluster Analysis Computerized, statistical medical data processing and models in biomedicine Epidemiologic Methods Humans Leukemia - epidemiology Likelihood Functions Medical sciences Medical statistics New York - epidemiology |
| title | A weighted average likelihood ratio test for spatial clustering of disease |
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