Argosomes: A Potential Vehicle for the Spread of Morphogens through Epithelia

The formation of morphogen gradients is essential for tissue patterning. Morphogens are released from producing cells and spread through adjacent tissue; paradoxically, however, many morphogens, including Wingless, associate tightly with the cell membrane. Here, we describe a novel cell biological m...

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Veröffentlicht in:	Cell 2001-09, Vol.106 (5), p.633-645
Hauptverfasser:	Greco, Valentina, Hannus, Michael, Eaton, Suzanne
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Cell Membrane Structures - physiology Cell Membrane Structures - ultrastructure Drosophila Drosophila melanogaster - growth & development Drosophila melanogaster - metabolism Drosophila Proteins Endosomes - metabolism Epithelium - metabolism Green Fluorescent Proteins Heparin Lyase - pharmacology Indicators and Reagents - metabolism Luminescent Proteins - metabolism Models, Biological Morphogenesis - physiology morphogens Proto-Oncogene Proteins - metabolism Transport Vesicles - physiology Transport Vesicles - ultrastructure Wnt1 Protein
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