Production of secretory IgA antibodies in plants

Functional antibodies produced in tobacco plants were first reported over a decade ago (1989). The basic protocol used to generate these ‘plantibodies’ involved the independent cloning of H and L chain antibody genes in Agrobacterium tumefaciens vectors, the transformation of plant tissue in vitro w...

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Veröffentlicht in:	Biomolecular Engineering 2001-10, Vol.18 (3), p.87-94
Hauptverfasser:	Larrick, James W, Yu, Lloyd, Naftzger, Clarissa, Jaiswal, Sudhir, Wycoff, Keith
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody Formation - immunology Apoplasm Bioreactors Gene Expression Regulation, Plant Glycosylation Plant biotechnology Plants - immunology Plants, Genetically Modified - immunology Recombinant Proteins - biosynthesis Recombinant Proteins - genetics Recombinant Proteins - immunology Secretory IgA Signal Transduction - immunology Streptococcus mutans
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