Suppression of chronic streptococcal cell wall‐induced arthritis in Lewis rats by liposomal clodronate

Objectives. To investigate the role of macrophages in the pathogenesis of chronic streptococcal cell wall (SCW)‐induced arthritis using liposomal clodronate. Methods. Female Lewis rats with SCW‐induced arthritis received a single intravenous injection of 20 mg of clodronate encapsulated within small...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Rheumatology (Oxford, England) England), 2001-09, Vol.40 (9), p.978-987
Hauptverfasser:	Richards, P. J., Williams, B. D., Williams, A. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ankle Joint - metabolism Ankle Joint - pathology Arthritis, Experimental - drug therapy Arthritis, Experimental - pathology Biological and medical sciences Clodronic Acid - administration & dosage Clodronic Acid - therapeutic use Disease Models, Animal Diseases of the osteoarticular system Drug Carriers Female Image Processing, Computer-Assisted Immunoenzyme Techniques Inflammatory joint diseases Injections, Intravenous Interleukin-1 - metabolism Interleukin-6 - metabolism Liposomal clodronate Liposomes macrophages Macrophages - drug effects Macrophages - pathology Matrix Metalloproteinase 9 - metabolism Medical sciences Rats Rats, Inbred Lew Streptococcal cell wall‐induced arthritis Streptococcus Tumor Necrosis Factor-alpha - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!