Essential control of an endothelial cell ISOC by the spectrin membrane skeleton

Mechanism(s) underlying activation of store-operated Ca2+ entry currents, ISOC, remain incompletely understood. F-actin configuration is an important determinant of channel function, although the nature of interaction between the cytoskeleton and ISOC channels is unknown. We examined whether the spe...

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Veröffentlicht in:	The Journal of cell biology 2001-09, Vol.154 (6), p.1225-1233
Hauptverfasser:	Wu, S, Sangerman, J, Li, M, Brough, G H, Goodman, S R, Stevens, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium Calcium - metabolism Calcium Channels - drug effects Cell Culture Techniques Cellular biology Cytoskeletal Proteins Cytoskeleton Electrophysiology Endothelium, Vascular - cytology Endothelium, Vascular - ultrastructure Humans Kinetics Lanthanum - pharmacology Membrane Proteins - metabolism Membrane Proteins - pharmacology Membrane Proteins - physiology Membranes Neuropeptides Patch-Clamp Techniques Rats Spectrin - metabolism Spectrin - pharmacology Spectrin - physiology Thapsigargin - pharmacology
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