Collagen type II C-telopeptide fragments as an index of cartilage degradation

We report the development of an assay for measurement of the urinary concentration of collagen type II C-telopeptide fragments. This assay was developed for providing a specific marker of joint metabolism. A monoclonal antibody, recognizing a linear six amino acid epitope from the middle region of t...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2001-09, Vol.29 (3), p.209-215
Hauptverfasser:	Christgau, S, Garnero, P, Fledelius, C, Moniz, C, Ensig, M, Gineyts, E, Rosenquist, C, Qvist, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Antibody Specificity Arthritis, Rheumatoid - pathology Arthritis, Rheumatoid - urine Biochemical marker Biological and medical sciences Biomarkers Cartilage - pathology Cartilage degradation Cells, Cultured Circadian Rhythm Collagen - analysis Collagen - immunology Collagen - urine Collagen Type I Collagen type II Collagen Type II - analysis Collagen Type II - immunology Collagen Type II - urine Enzyme-Linked Immunosorbent Assay Female Immunoassay In Vitro Techniques Investigative techniques, diagnostic techniques (general aspects) Medical sciences Mice Mice, Inbred BALB C Osteitis Deformans - pathology Osteitis Deformans - urine Osteoarthritis - pathology Osteoarthritis - urine Osteoarticular system. Muscles Osteoclasts - chemistry Osteoclasts - cytology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Peptide Fragments - analysis Peptide Fragments - immunology Peptide Fragments - urine Peptides - analysis Peptides - immunology Peptides - urine Rabbits
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