Attenuation of a Brucella abortus mutant lacking a major 25 kDa outer membrane protein in cattle

To determine the virulence of a Brucella abortus mutant, BA25, lacking a major 25 kd outer membrane protein (Omp25) in cattle. 20 mixed-breed heifers in late gestation. 10 heifers were inoculated with 1 x 10(7) colony-forming units of the Omp25 mutant via the conjunctival sac, and an equal number we...

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