$Spatial and temporal gene expression in chondrogenesis during fracture healing and the effects of basic fibroblast growth factor$

Spatial and temporal gene expression in chondrogenesis during fracture healing and the effects of basic fibroblast growth factor

Chondrogenesis is an essential component of endochondral fracture healing, though the molecular and cellular events by which it is regulated have not been fully elucidated. In this study, we used a rat model of closed fracture healing to determine the spatial and temporal expression of genes for car...

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Veröffentlicht in:	Journal of orthopaedic research 2001-09, Vol.19 (5), p.935-944
Hauptverfasser:	Nakajima, Fumitake, Ogasawara, Akira, Goto, Ken-ichiro, Moriya, Hideshige, Ninomiya, Yoshifumi, Einhorn, Thomas A, Yamazaki, Masashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cartilage - chemistry Cartilage - physiology Chondrocytes - chemistry Chondrocytes - physiology Chondrogenesis - drug effects Chondrogenesis - physiology Disease Models, Animal Fibroblast Growth Factor 2 - pharmacokinetics Fracture Healing - drug effects Fractures, Closed - drug therapy Fractures, Closed - physiopathology Gene Expression - drug effects Iodine Radioisotopes Male Procollagen - genetics Proliferating Cell Nuclear Antigen - analysis Rats Rats, Sprague-Dawley RNA, Messenger - analysis
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