Cytokine responses to Der p 1 and Der p 7: house dust mite allergens with different IgE-binding activities

Background There is very limited information comparing T‐cell responses to different house dust mite (HDM) allergens even though T cells are essential in the initiation and regulation of immunoglobulin (Ig) E synthesis and eosinophilia. Objective To compare the level of T‐cell proliferation and cyto...

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Veröffentlicht in:	Clinical and experimental allergy 2000-07, Vol.30 (7), p.934-943
Hauptverfasser:	HALES, B. J, SHEN, H.-D, THOMAS, W. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergens - immunology Allergens - pharmacology Allergic diseases Animals Antibody Affinity - immunology Antigens, Dermatophagoides Biological and medical sciences cytokine cytokines Cytokines - biosynthesis Der p 1 Der p 1 antigen Der p 7 Der p 7 antigen Dermatophagoides pteronyssinus Dose-Response Relationship, Drug Female g-Interferon General aspects Glycoproteins - immunology Glycoproteins - pharmacology house dust mite Humans Hypersensitivity - etiology Hypersensitivity - immunology IgE Immunoglobulin E - immunology Immunopathology Interferon-gamma - biosynthesis Interleukin-5 - biosynthesis Lymphocyte Activation - drug effects Lymphocyte Activation - immunology Male Medical sciences Middle Aged Mites Pyroglyphidae T cells T-Lymphocytes - drug effects T-Lymphocytes - immunology
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