Thonningianins A and B, New Antioxidants from the African Medicinal Herb Thonningia sanguinea

Two new ellagitannins, thonningianins A (1) and B (2), have been isolated from the African medicinal herb Thonningia sanguinea and their structures elucidated by interpretation of spectroscopic data. Both 1 and 2 showed strong free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (D...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2000-05, Vol.63 (5), p.676-679
Hauptverfasser:	OHTANI, Ikuko I., GOTOH, Naomi, TANAKA, Junichi, HIGA, Tatsuo, GYAMFI, Maxwell A., ANIYA, Yoko
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa Antioxidants - isolation & purification Antioxidants - pharmacology Bepridil - analogs & derivatives Bepridil - chemistry Biphenyl Compounds Free Radical Scavengers - isolation & purification Free Radical Scavengers - pharmacology Free Radicals - chemistry Hydrolyzable Tannins Magnetic Resonance Spectroscopy Picrates Plants, Medicinal - chemistry Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Tannins - isolation & purification Tannins - pharmacology
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Beschreibung
Zusammenfassung:	Two new ellagitannins, thonningianins A (1) and B (2), have been isolated from the African medicinal herb Thonningia sanguinea and their structures elucidated by interpretation of spectroscopic data. Both 1 and 2 showed strong free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) as shown by ESR analysis.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np990396w