Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET)

Neuropathology studies show that patients with mild cognitive impairment (MCI) and Alzheimer's disease typically have lesions of the entorhinal cortex (EC), hippocampus (Hip), and temporal neocortex. Related observations with in vivo imaging have enabled the prediction of dementia from MCI. Alt...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2001-09, Vol.98 (19), p.10966-10971
Hauptverfasser:	de Leon, M J, Convit, A, Wolf, O T, Tarshish, C Y, DeSanti, S, Rusinek, H, Tsui, W, Kandil, E, Scherer, A J, Roche, A, Imossi, A, Thorn, E, Bobinski, M, Caraos, C, Lesbre, P, Schlyer, D, Poirier, J, Reisberg, B, Fowler, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Apolipoproteins E - metabolism Brain - diagnostic imaging Cognition Disorders - diagnostic imaging Cognition Disorders - metabolism Entorhinal Cortex - diagnostic imaging Female Fluorodeoxyglucose F18 - metabolism Follow-Up Studies Hippocampus - diagnostic imaging Humans Longitudinal Studies Magnetic Resonance Imaging - methods Male Middle Aged Predictive Value of Tests Radiography Tomography, Emission-Computed - methods
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