Pulmonary alveolar proteinosis causing severe hypoxemic respiratory failure treated with sequential whole-lung lavage utilizing venovenous extracorporeal membrane oxygenation a case report and review
Pulmonary alveolar proteinosis is characterized by the accumulation of proteinaceous material in the alveoli leading to varying degrees of impairment in gas exchange. Generally, the degree of hypoxemia is mild, and it is rare to have respiratory failure requiring mechanical ventilation. We present a...
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| Veröffentlicht in: | Chest 2001-09, Vol.120 (3), p.1024-1026 |
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| container_title | Chest |
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| creator | COHEN, Elliott S ELPERN, Ellen SILVER, Michael R |
| description | Pulmonary alveolar proteinosis is characterized by the accumulation of proteinaceous material in the alveoli leading to varying degrees of impairment in gas exchange. Generally, the degree of hypoxemia is mild, and it is rare to have respiratory failure requiring mechanical ventilation. We present a 53-year-old woman with the most severe degree of hypoxemia associated with alveolar proteinosis reported in the English-language adult literature. Her therapy of sequential whole-lung lavage performed while receiving venovenous extracorporeal membrane oxygenation in one operative session is the first reported successful use of this approach. |
| doi_str_mv | 10.1378/chest.120.3.1024 |
| format | Article |
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Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Emergency and intensive respiratory care</subject><subject>Extracorporeal Membrane Oxygenation - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Hypoxia - etiology</subject><subject>Intensive care medicine</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pulmonary Alveolar Proteinosis - complications</subject><subject>Pulmonary Alveolar Proteinosis - diagnostic imaging</subject><subject>Respiratory Insufficiency - etiology</subject><subject>Respiratory Insufficiency - therapy</subject><subject>Therapeutic Irrigation - methods</subject><subject>Tomography, X-Ray Computed</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkU2PFCEQhonRuOPq3ZMhJnrrERqabo5ms34km-hBzx2arplhQ0MLdM-Mf9C_ZW0cYyIJoQhPvVS9RchLzrZctN07e4BctrxmW7HlrJaPyIZrwSvRSPGYbBjjdSWUrq_Is5zvGd65Vk_JFecNLik35NfXxU8xmHSmxq8QvUl0TrGACzG7TK1Zsgt7mmGFBPRwnuMJJmdpgjy7ZErEzJ1xfsHXksAUGOnRlQNm_FggFGc8PR6ih8ovqOPNavZAl-K8-_kgvEKID3vJFE4lGRvTHFHH0wmmIZkANJ7OewimuBiowYoy4O8IFWrCiOHq4PicPNkZn-HF5bwm3z_cfrv5VN19-fj55v1dNddKlkpzaHkn9cB1s-s4jKpp0AzZNDUbhnHXKm076GzbjTUfrLZqZMOou8GaQTLQ4pq8_aOLJmF_ufSTyxa8x0Kxh77lXHV1wxF8_R94H5cUsLa-ZqyRTCiG0KsLtAwTjP2c3ISj6P_OB4E3F8Bka_wO_bAu_-MkU0p0rfgN-BmnNQ</recordid><startdate>20010901</startdate><enddate>20010901</enddate><creator>COHEN, Elliott S</creator><creator>ELPERN, Ellen</creator><creator>SILVER, Michael R</creator><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20010901</creationdate><title>Pulmonary alveolar proteinosis causing severe hypoxemic respiratory failure treated with sequential whole-lung lavage utilizing venovenous extracorporeal membrane oxygenation a case report and review</title><author>COHEN, Elliott S ; ELPERN, Ellen ; SILVER, Michael R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p264t-91e71849b195f81ed65511545520bbdf769c8e8c78d21bc9c6d0bd98bcab40e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Anesthesia. 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| ispartof | Chest, 2001-09, Vol.120 (3), p.1024-1026 |
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| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Emergency and intensive respiratory care Extracorporeal Membrane Oxygenation - methods Female Humans Hypoxia - etiology Intensive care medicine Medical sciences Middle Aged Pulmonary Alveolar Proteinosis - complications Pulmonary Alveolar Proteinosis - diagnostic imaging Respiratory Insufficiency - etiology Respiratory Insufficiency - therapy Therapeutic Irrigation - methods Tomography, X-Ray Computed |
| title | Pulmonary alveolar proteinosis causing severe hypoxemic respiratory failure treated with sequential whole-lung lavage utilizing venovenous extracorporeal membrane oxygenation a case report and review |
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