GVHD‐Associated Enteropathy and Endotoxemia in F1‐Hybrid Recipients of NK1.1‐Depleted Grafts

Our previous work using a C57BL/6→(C57BL/6 × DBA/2)F1‐hybrid model of acute GVHD showed that mortality can be completely prevented if grafts are depleted of NK1.1+ cells in vitro. To achieve this protection, it was necessary to inject the donors with polyinosinic:polycytidylic acid 18 h before the g...

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Veröffentlicht in:	Scandinavian journal of immunology 2001-10, Vol.54 (4), p.375-382
Hauptverfasser:	Ellison, C. A., Amadeo, R. J. J., Gartner, J. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens - immunology Antigens, Ly Antigens, Surface Cell Transplantation Cytotoxicity, Immunologic Endotoxemia - blood Endotoxemia - immunology Female Graft vs Host Disease - blood Graft vs Host Disease - immunology Graft vs Host Disease - mortality Graft vs Host Disease - pathology Ileum - immunology Ileum - pathology Intestinal Mucosa - pathology Killer Cells, Natural - immunology Lectins, C-Type Lipopolysaccharides - blood Lymph Nodes - cytology Mice Mice, Inbred BALB C Mice, Inbred C3H Mice, Inbred C57BL Mice, Inbred DBA NK Cell Lectin-Like Receptor Subfamily B Proteins - immunology Tumor Cells, Cultured Weight Loss
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