Antinociceptive effects of tetrahydrocannabinol side chain analogs: dependence upon route of administration

The role of flexibility of the alkyl side chain in the tetrahydrocannabinols to cannabinoid activity has been delineated in previous studies with side chain analogs of Δ 8-tetrahydrocannabinol with double or triple bonds. This study investigated the site of antinociceptive action for these analogs t...

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Veröffentlicht in:	European journal of pharmacology 2000-06, Vol.397 (2), p.319-326
Hauptverfasser:	Wiley, Jenny L, Patrick, Gray S, Crocker, Peter C, Saha, Bijali, Razdan, Raj K, Martin, Billy R
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Analgesics, Non-Narcotic - chemistry Analgesics, Non-Narcotic - pharmacology Animals Antinociception Biological and medical sciences Cannabinoid Dronabinol - chemistry Dronabinol - pharmacology Drug Administration Routes Injections, Intraventricular Injections, Spinal Intrahecal Intraventricular Male Medical sciences Mice Mice, Inbred ICR Neuropharmacology Nociceptors - drug effects Pain - prevention & control Pain Measurement Pharmacology. Drug treatments Structure-Activity Relationship Tetrahydrocannabinol
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