Increased levels of immune inhibitory CD34 + progenitor cells in the peripheral blood of patients with node positive head and neck squamous cell carcinomas and the ability of these CD34 + cells to differentiate into immune stimulatory dendritic cells

Objectives: This study determined whether mobilization of immune inhibitory CD34 + cells by head and neck squamous cell carcinomas (HNSCC) is most prominent in patients who are node positive and whether these CD34 + cells could differentiate into immune stimulatory dendritic cells. Study Design and...

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Veröffentlicht in:	Otolaryngology-head and neck surgery 2001-09, Vol.125 (3), p.205-212
Hauptverfasser:	Lathers, Deanne M.R., Achille, Nicholas, Kolesiak, Kristin, Hulett, Kevin, Sparano, Anthony, Petruzzelli, Guy J., Young, M.Rita I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen Presentation Antigens, CD34 - blood Antigens, CD34 - physiology Carcinoma, Squamous Cell - blood Carcinoma, Squamous Cell - immunology Cell Differentiation Dendritic Cells - immunology Granulocyte-Macrophage Colony-Stimulating Factor - blood Head and Neck Neoplasms - blood Head and Neck Neoplasms - immunology Humans Interferon-gamma - secretion Neoplasm Recurrence, Local - immunology T-Lymphocytes - metabolism
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