The NK-2 homeobox gene scarecrow ( scro) is expressed in pharynx, ventral nerve cord and brain of Drosophila embryos
Members of the NK homeobox family have been widely conserved during evolution. Here we describe the sequence and expression of a novel Drosophila NK-2 homeobox gene, named scarecrow ( scro), which shows considerable homology to vertebrate Nkx-2.1. During embryogenesis, scro expression is initially o...
Gespeichert in:
| Veröffentlicht in: | Mechanisms of development 2000-06, Vol.94 (1), p.237-241 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 241 |
|---|---|
| container_issue | 1 |
| container_start_page | 237 |
| container_title | Mechanisms of development |
| container_volume | 94 |
| creator | Zaffran, Stéphane Das, Gishnu Frasch, Manfred |
| description | Members of the NK homeobox family have been widely conserved during evolution. Here we describe the sequence and expression of a novel
Drosophila NK-2 homeobox gene, named
scarecrow (
scro), which shows considerable homology to vertebrate
Nkx-2.1. During embryogenesis,
scro expression is initially observed in the pharyngeal primordia and later maintained in the pharynx. During band germ retraction,
scro expression appears in two bilateral clusters of procephalic neuroblasts that give rise to distinct neuronal clusters in the brain. In addition,
scro expression is observed in segmental clusters of neuronal precursors in the ventral nerve cord. In larval stages,
scro expression occurs in portions of the optic lobe regions. These observations indicate that
scro and vertebrate
Nkx2.1 share similarities both in terms of their sequence and their expression patterns. |
| doi_str_mv | 10.1016/S0925-4773(00)00298-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71162047</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0925477300002987</els_id><sourcerecordid>71162047</sourcerecordid><originalsourceid>FETCH-LOGICAL-c460t-c697c74d1dfa08c76b59100099380cd02d90c0974f5ed70a77f36bed33b95fb13</originalsourceid><addsrcrecordid>eNqFkE1P4zAQhi0Egi7sTwD5hEDawDhfjk8IsbAgquVA92w59oQaJXGw01L-_boUIW6cZg7PO6P3IeSQwRkDVp4_gkiLJOc8OwE4BUhFlfAtMmEVT5MyK8ptMvlE9siPEJ4BgLGS7ZI9BlWeAhcTMs7mSP_eJymduw5d7Vb0CXukQSuP2rtXehJ3706pDRRXg8cQ0FDb02Gu_Fu_-kWX2I9etbRHv0SqnTdU9YbWXkXKNfS3d8ENc9sqil3t31w4IDuNagP-_Jj75N_N9ezqNpk-_Lm7upwmOi9hTHQpuOa5YaZRUGle1oVgsYQQWQXaQGoEaBA8bwo0HBTnTVbWaLKsFkVTs2yfHG_uDt69LDCMsrNBY9uqHt0iSB51pJDzCBYbMDYNwWMjB2-72E8ykGvd8l23XLuUAPJdt1znjj4eLOoOzZfUxm8ELjYAxppLi14GbbHXaGzUO0rj7Dcv_gMj2o85</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71162047</pqid></control><display><type>article</type><title>The NK-2 homeobox gene scarecrow ( scro) is expressed in pharynx, ventral nerve cord and brain of Drosophila embryos</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Zaffran, Stéphane ; Das, Gishnu ; Frasch, Manfred</creator><creatorcontrib>Zaffran, Stéphane ; Das, Gishnu ; Frasch, Manfred</creatorcontrib><description>Members of the NK homeobox family have been widely conserved during evolution. Here we describe the sequence and expression of a novel
Drosophila NK-2 homeobox gene, named
scarecrow (
scro), which shows considerable homology to vertebrate
Nkx-2.1. During embryogenesis,
scro expression is initially observed in the pharyngeal primordia and later maintained in the pharynx. During band germ retraction,
scro expression appears in two bilateral clusters of procephalic neuroblasts that give rise to distinct neuronal clusters in the brain. In addition,
scro expression is observed in segmental clusters of neuronal precursors in the ventral nerve cord. In larval stages,
scro expression occurs in portions of the optic lobe regions. These observations indicate that
scro and vertebrate
Nkx2.1 share similarities both in terms of their sequence and their expression patterns.</description><identifier>ISSN: 0925-4773</identifier><identifier>EISSN: 1872-6356</identifier><identifier>DOI: 10.1016/S0925-4773(00)00298-7</identifier><identifier>PMID: 10842079</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Amino Acid Sequence ; Animals ; Brain - embryology ; Central nervous system ; Central Nervous System - embryology ; Drosophila ; Drosophila - embryology ; Drosophila - genetics ; Embryo, Nonmammalian ; Ganglia, Invertebrate - embryology ; Gene Expression Regulation, Developmental ; Homeodomain ; Homeodomain Proteins - genetics ; Homeodomain Proteins - metabolism ; Molecular Sequence Data ; NK-2 ; Nuclear Proteins - genetics ; Nuclear Proteins - metabolism ; Optic lobe ; Pharynx ; Pharynx - embryology ; Sequence Homology, Amino Acid ; Thyroid Nuclear Factor 1 ; Transcription Factors - genetics ; Transcription Factors - metabolism</subject><ispartof>Mechanisms of development, 2000-06, Vol.94 (1), p.237-241</ispartof><rights>2000 Elsevier Science Ireland Ltd</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c460t-c697c74d1dfa08c76b59100099380cd02d90c0974f5ed70a77f36bed33b95fb13</citedby><cites>FETCH-LOGICAL-c460t-c697c74d1dfa08c76b59100099380cd02d90c0974f5ed70a77f36bed33b95fb13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0925-4773(00)00298-7$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10842079$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zaffran, Stéphane</creatorcontrib><creatorcontrib>Das, Gishnu</creatorcontrib><creatorcontrib>Frasch, Manfred</creatorcontrib><title>The NK-2 homeobox gene scarecrow ( scro) is expressed in pharynx, ventral nerve cord and brain of Drosophila embryos</title><title>Mechanisms of development</title><addtitle>Mech Dev</addtitle><description>Members of the NK homeobox family have been widely conserved during evolution. Here we describe the sequence and expression of a novel
Drosophila NK-2 homeobox gene, named
scarecrow (
scro), which shows considerable homology to vertebrate
Nkx-2.1. During embryogenesis,
scro expression is initially observed in the pharyngeal primordia and later maintained in the pharynx. During band germ retraction,
scro expression appears in two bilateral clusters of procephalic neuroblasts that give rise to distinct neuronal clusters in the brain. In addition,
scro expression is observed in segmental clusters of neuronal precursors in the ventral nerve cord. In larval stages,
scro expression occurs in portions of the optic lobe regions. These observations indicate that
scro and vertebrate
Nkx2.1 share similarities both in terms of their sequence and their expression patterns.</description><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Brain - embryology</subject><subject>Central nervous system</subject><subject>Central Nervous System - embryology</subject><subject>Drosophila</subject><subject>Drosophila - embryology</subject><subject>Drosophila - genetics</subject><subject>Embryo, Nonmammalian</subject><subject>Ganglia, Invertebrate - embryology</subject><subject>Gene Expression Regulation, Developmental</subject><subject>Homeodomain</subject><subject>Homeodomain Proteins - genetics</subject><subject>Homeodomain Proteins - metabolism</subject><subject>Molecular Sequence Data</subject><subject>NK-2</subject><subject>Nuclear Proteins - genetics</subject><subject>Nuclear Proteins - metabolism</subject><subject>Optic lobe</subject><subject>Pharynx</subject><subject>Pharynx - embryology</subject><subject>Sequence Homology, Amino Acid</subject><subject>Thyroid Nuclear Factor 1</subject><subject>Transcription Factors - genetics</subject><subject>Transcription Factors - metabolism</subject><issn>0925-4773</issn><issn>1872-6356</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1P4zAQhi0Egi7sTwD5hEDawDhfjk8IsbAgquVA92w59oQaJXGw01L-_boUIW6cZg7PO6P3IeSQwRkDVp4_gkiLJOc8OwE4BUhFlfAtMmEVT5MyK8ptMvlE9siPEJ4BgLGS7ZI9BlWeAhcTMs7mSP_eJymduw5d7Vb0CXukQSuP2rtXehJ3706pDRRXg8cQ0FDb02Gu_Fu_-kWX2I9etbRHv0SqnTdU9YbWXkXKNfS3d8ENc9sqil3t31w4IDuNagP-_Jj75N_N9ezqNpk-_Lm7upwmOi9hTHQpuOa5YaZRUGle1oVgsYQQWQXaQGoEaBA8bwo0HBTnTVbWaLKsFkVTs2yfHG_uDt69LDCMsrNBY9uqHt0iSB51pJDzCBYbMDYNwWMjB2-72E8ykGvd8l23XLuUAPJdt1znjj4eLOoOzZfUxm8ELjYAxppLi14GbbHXaGzUO0rj7Dcv_gMj2o85</recordid><startdate>20000601</startdate><enddate>20000601</enddate><creator>Zaffran, Stéphane</creator><creator>Das, Gishnu</creator><creator>Frasch, Manfred</creator><general>Elsevier Ireland Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20000601</creationdate><title>The NK-2 homeobox gene scarecrow ( scro) is expressed in pharynx, ventral nerve cord and brain of Drosophila embryos</title><author>Zaffran, Stéphane ; Das, Gishnu ; Frasch, Manfred</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c460t-c697c74d1dfa08c76b59100099380cd02d90c0974f5ed70a77f36bed33b95fb13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Brain - embryology</topic><topic>Central nervous system</topic><topic>Central Nervous System - embryology</topic><topic>Drosophila</topic><topic>Drosophila - embryology</topic><topic>Drosophila - genetics</topic><topic>Embryo, Nonmammalian</topic><topic>Ganglia, Invertebrate - embryology</topic><topic>Gene Expression Regulation, Developmental</topic><topic>Homeodomain</topic><topic>Homeodomain Proteins - genetics</topic><topic>Homeodomain Proteins - metabolism</topic><topic>Molecular Sequence Data</topic><topic>NK-2</topic><topic>Nuclear Proteins - genetics</topic><topic>Nuclear Proteins - metabolism</topic><topic>Optic lobe</topic><topic>Pharynx</topic><topic>Pharynx - embryology</topic><topic>Sequence Homology, Amino Acid</topic><topic>Thyroid Nuclear Factor 1</topic><topic>Transcription Factors - genetics</topic><topic>Transcription Factors - metabolism</topic><toplevel>online_resources</toplevel><creatorcontrib>Zaffran, Stéphane</creatorcontrib><creatorcontrib>Das, Gishnu</creatorcontrib><creatorcontrib>Frasch, Manfred</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Mechanisms of development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zaffran, Stéphane</au><au>Das, Gishnu</au><au>Frasch, Manfred</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The NK-2 homeobox gene scarecrow ( scro) is expressed in pharynx, ventral nerve cord and brain of Drosophila embryos</atitle><jtitle>Mechanisms of development</jtitle><addtitle>Mech Dev</addtitle><date>2000-06-01</date><risdate>2000</risdate><volume>94</volume><issue>1</issue><spage>237</spage><epage>241</epage><pages>237-241</pages><issn>0925-4773</issn><eissn>1872-6356</eissn><abstract>Members of the NK homeobox family have been widely conserved during evolution. Here we describe the sequence and expression of a novel
Drosophila NK-2 homeobox gene, named
scarecrow (
scro), which shows considerable homology to vertebrate
Nkx-2.1. During embryogenesis,
scro expression is initially observed in the pharyngeal primordia and later maintained in the pharynx. During band germ retraction,
scro expression appears in two bilateral clusters of procephalic neuroblasts that give rise to distinct neuronal clusters in the brain. In addition,
scro expression is observed in segmental clusters of neuronal precursors in the ventral nerve cord. In larval stages,
scro expression occurs in portions of the optic lobe regions. These observations indicate that
scro and vertebrate
Nkx2.1 share similarities both in terms of their sequence and their expression patterns.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>10842079</pmid><doi>10.1016/S0925-4773(00)00298-7</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0925-4773 |
| ispartof | Mechanisms of development, 2000-06, Vol.94 (1), p.237-241 |
| issn | 0925-4773 1872-6356 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71162047 |
| source | MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals |
| subjects | Amino Acid Sequence Animals Brain - embryology Central nervous system Central Nervous System - embryology Drosophila Drosophila - embryology Drosophila - genetics Embryo, Nonmammalian Ganglia, Invertebrate - embryology Gene Expression Regulation, Developmental Homeodomain Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Molecular Sequence Data NK-2 Nuclear Proteins - genetics Nuclear Proteins - metabolism Optic lobe Pharynx Pharynx - embryology Sequence Homology, Amino Acid Thyroid Nuclear Factor 1 Transcription Factors - genetics Transcription Factors - metabolism |
| title | The NK-2 homeobox gene scarecrow ( scro) is expressed in pharynx, ventral nerve cord and brain of Drosophila embryos |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T09%3A00%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20NK-2%20homeobox%20gene%20scarecrow%20(%20scro)%20is%20expressed%20in%20pharynx,%20ventral%20nerve%20cord%20and%20brain%20of%20Drosophila%20embryos&rft.jtitle=Mechanisms%20of%20development&rft.au=Zaffran,%20St%C3%A9phane&rft.date=2000-06-01&rft.volume=94&rft.issue=1&rft.spage=237&rft.epage=241&rft.pages=237-241&rft.issn=0925-4773&rft.eissn=1872-6356&rft_id=info:doi/10.1016/S0925-4773(00)00298-7&rft_dat=%3Cproquest_cross%3E71162047%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=71162047&rft_id=info:pmid/10842079&rft_els_id=S0925477300002987&rfr_iscdi=true |