CCR6 Mediates Dendritic Cell Localization, Lymphocyte Homeostasis, and Immune Responses in Mucosal Tissue

Chemokine-directed migration of leukocyte subsets may contribute to the qualitative differences between systemic and mucosal immunity. Here, we demonstrate that in mice lacking the chemokine receptor CCR6, dendritic cells expressing CD11c and CD11b are absent from the subepithelial dome of Peyer...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2000-05, Vol.12 (5), p.495-503
Hauptverfasser:	Cook, Donald N, Prosser, Dina M, Forster, Reinhold, Zhang, Jiwen, Kuklin, Nelly A, Abbondanzo, Susan J, Niu, Xiao-Da, Chen, Shu-Cheng, Manfra, Denise J, Wiekowski, Maria T, Sullivan, Lee M, Smith, Sidney R, Greenberg, Harry B, Narula, Satwant K, Lipp, Martin, Lira, Sergio A
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals CCR6 protein CD11 Antigens - immunology CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Cell Movement - immunology Dendritic Cells - immunology Dendritic Cells - pathology Immunity, Mucosal Mice Mice, Knockout Receptors, CCR6 Receptors, Chemokine - immunology
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