Large conformational changes in the maturation of a simple RNA virus, Nudaurelia capensis omega virus (NomegaV)

An assembly intermediate of a small, non-enveloped RNA virus has been discovered that exhibits striking differences from the mature virion. Virus-like particles (VLPs) of Nudaurelia capensis omega virus (NomegaV), a T=4 icosahedral virus infecting Lepidoptera insects, were produced in insect cells u...

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Veröffentlicht in:	Journal of molecular biology 2000-06, Vol.299 (3), p.573-584
Hauptverfasser:	Canady, M.A, Tihova, M, Hanzlik, T.N, Johnson, J.E, Yeager, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Baculovirus Binding Sites capsid Capsid - chemistry Capsid - genetics Capsid - metabolism Capsid - ultrastructure Cell Line Cryoelectron Microscopy Dimerization Hydrogen-Ion Concentration insect viruses Insect Viruses - chemistry Insect Viruses - genetics Insect Viruses - metabolism Insect Viruses - ultrastructure Models, Molecular Molecular Weight Nudaurelia capensis ^w virus Nudaurelia capensis b virus procapsids Protein Conformation Protein Precursors - chemistry Protein Precursors - genetics Protein Precursors - metabolism Protein Precursors - ultrastructure Protein Processing, Post-Translational Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - metabolism Recombinant Proteins - ultrastructure RNA Viruses - chemistry RNA Viruses - genetics RNA Viruses - metabolism RNA Viruses - ultrastructure Rotation Spodoptera Static Electricity ultrastructure viral morphology Virus Assembly virus replication virus-like particles
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