Use of a Mouse Lung Challenge Model to Identify Antigens Protective against Chlamydia pneumoniae Lung Infection

Chlamydia pneumoniae is emerging as a significant human pathogen. Infection causes a range of respiratory tract diseases and is associated with atherosclerosis. A vaccine could provide a considerable public health benefit; however, antigens able to elicit a protective immune response are largely unk...

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Veröffentlicht in:	The Journal of infectious diseases 2000-06, Vol.181 (Supplement-3), p.S544-S551
Hauptverfasser:	Murdin, Andrew D., Dunn, Pamela, Sodoyer, Regis, Wang, Joe, Caterini, Judy, Brunham, Robert C., Aujame, Luc, Oomen, Ray
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Antigens, Bacterial - immunology Bacterial Outer Membrane Proteins - genetics Bacterial Outer Membrane Proteins - immunology Bacterial Proteins - genetics Bacterial Proteins - immunology Bacterial Vaccines - immunology Bacteriology Biological and medical sciences Chlamydia Chlamydia Infections - prevention & control Chlamydia pneumoniae Chlamydophila pneumoniae Chlamydophila pneumoniae - genetics Chlamydophila pneumoniae - immunology Disease Models, Animal DNA Fundamental and applied biological sciences. Psychology Humans Immune response Immunization Infections Lung - microbiology Lung Diseases - prevention & control Lungs Mice Mice, Inbred BALB C Microbiology Open reading frames Open Reading Frames - genetics Open Reading Frames - immunology Potential for a Chlamydia pneumoniae Vaccine Respiratory Tract Infections - prevention & control Vaccination Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, DNA - immunology
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