Molecular pathophysiology and targeted therapeutics for muscular dystrophy

Experimental therapeutics of the muscular dystrophies has made impressive advances on several fronts. Adeno-associated virus has emerged as the clear ‘vector of choice’ for muscle gene delivery, with successful functional rescue of dystrophic muscle in rodent models. Correction of the dystrophin gen...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Trends in Pharmacological Sciences 2001-09, Vol.22 (9), p.465-470
Hauptverfasser:	Hoffman, Eric P, Dressman, Devin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adeno-associated virus Adrenal Cortex Hormones - therapeutic use Animals Ca2+ ATPases Ca2+ binding proteins Ca2+ signalling Cytoskeletal Proteins - deficiency Cytoskeletal Proteins - genetics Cytoskeletal Proteins - physiology Dystrophin - deficiency Dystrophin - genetics Dystrophin - physiology endoplasmic reticulum Humans InsP3 receptors Membrane Glycoproteins - deficiency Membrane Glycoproteins - genetics Membrane Glycoproteins - physiology Muscular Dystrophies - drug therapy Muscular Dystrophies - genetics Muscular Dystrophies - physiopathology ryanodine receptors Sarcoglycans
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!