Efficacy of ultrasound-guided fine-needle aspiration biopsy in the diagnosis of complex thyroid nodules
Cystic thyroid nodules are considered to be one of the major causes of nondiagnostic and false-negative results on conventional fine-needle aspiration biopsy, thus limiting the potential of this method for the evaluation of complex (solid-cystic) thyroid nodules. Although ultrasound-guided fine-need...
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Veröffentlicht in: | The journal of clinical endocrinology and metabolism 2001-09, Vol.86 (9), p.4089-4091 |
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creator | BRAGA, Milena CAVALCANTI, Teresa Cristina MARTINS COLLACO, Luiz GRAF, Hans |
description | Cystic thyroid nodules are considered to be one of the major causes of nondiagnostic and false-negative results on conventional fine-needle aspiration biopsy, thus limiting the potential of this method for the evaluation of complex (solid-cystic) thyroid nodules. Although ultrasound-guided fine-needle aspiration biopsy has emerged as a highly effective diagnostic method for the assessment of nonpalpable and difficult to palpate nodules, its role in complex nodules has not yet been carefully evaluated. In this study, we report the efficacy of ultrasound-guided fine-needle aspiration biopsy in 124 complex nodules in 113 patients. This method proved to be highly effective, yielding a satisfactory specimen for cytological evaluation in 94% of the nodules, suggesting that it is an excellent modality for the evaluation of complex nodules and also for the reevaluation of those nodules with a nondiagnostic result on conventional fine-needle aspiration biopsy. |
doi_str_mv | 10.1210/jc.86.9.4089 |
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Although ultrasound-guided fine-needle aspiration biopsy has emerged as a highly effective diagnostic method for the assessment of nonpalpable and difficult to palpate nodules, its role in complex nodules has not yet been carefully evaluated. In this study, we report the efficacy of ultrasound-guided fine-needle aspiration biopsy in 124 complex nodules in 113 patients. This method proved to be highly effective, yielding a satisfactory specimen for cytological evaluation in 94% of the nodules, suggesting that it is an excellent modality for the evaluation of complex nodules and also for the reevaluation of those nodules with a nondiagnostic result on conventional fine-needle aspiration biopsy.</description><identifier>ISSN: 0021-972X</identifier><identifier>EISSN: 1945-7197</identifier><identifier>DOI: 10.1210/jc.86.9.4089</identifier><identifier>PMID: 11549630</identifier><identifier>CODEN: JCEMAZ</identifier><language>eng</language><publisher>Bethesda, MD: Endocrine Society</publisher><subject>Adult ; Biological and medical sciences ; Biopsy, Needle - instrumentation ; Endocrinology ; Female ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Middle Aged ; Pathology. Cytology. Biochemistry. Spectrometry. 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Although ultrasound-guided fine-needle aspiration biopsy has emerged as a highly effective diagnostic method for the assessment of nonpalpable and difficult to palpate nodules, its role in complex nodules has not yet been carefully evaluated. In this study, we report the efficacy of ultrasound-guided fine-needle aspiration biopsy in 124 complex nodules in 113 patients. This method proved to be highly effective, yielding a satisfactory specimen for cytological evaluation in 94% of the nodules, suggesting that it is an excellent modality for the evaluation of complex nodules and also for the reevaluation of those nodules with a nondiagnostic result on conventional fine-needle aspiration biopsy.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Needle - instrumentation</subject><subject>Endocrinology</subject><subject>Female</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Prospective Studies</subject><subject>Thyroid Nodule - diagnostic imaging</subject><subject>Thyroid Nodule - pathology</subject><subject>Thyroid Nodule - surgery</subject><subject>Tropical medicine</subject><subject>Ultrasonography</subject><issn>0021-972X</issn><issn>1945-7197</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0M1LxDAQBfAgiruu3jxLLnprTdK0aY8i6wcseFHwVqbJZM3STWrTgv3vrbjiaQ7vx4M3hFxylnLB2e1Op2WRVqlkZXVElrySeaJ4pY7JkjHBk0qJ9wU5i3HHGJcyz07JgvNcVkXGlmS7ttZp0BMNlo7t0EMMozfJdnQGDbXOY-IRTYsUYud6GFzwtHGhixN1ng4fSI2DrQ_RxZ8OHfZdi19zMPXBGeqDGVuM5-TEQhvx4nBX5O1h_Xr_lGxeHp_v7zaJFlwMCQAUtlQiL3mJjUGFMldcCqNMAcBLpllZVFmmDMuZhULbBgXMGhvZGMWyFbn57e368DliHOq9ixrbFjyGMdZqnp4XlZzh1QGOzR5N3fVuD_1U_71mBtcHAFFDa3vw2sV_J7koZaGyb67ndBA</recordid><startdate>20010901</startdate><enddate>20010901</enddate><creator>BRAGA, Milena</creator><creator>CAVALCANTI, Teresa Cristina</creator><creator>MARTINS COLLACO, Luiz</creator><creator>GRAF, Hans</creator><general>Endocrine Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20010901</creationdate><title>Efficacy of ultrasound-guided fine-needle aspiration biopsy in the diagnosis of complex thyroid nodules</title><author>BRAGA, Milena ; CAVALCANTI, Teresa Cristina ; MARTINS COLLACO, Luiz ; GRAF, Hans</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c212t-aaa6f8725818ebde7e457142d7d6aa180c0869337d050fa6cfbe2a581eb4bd703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Needle - instrumentation</topic><topic>Endocrinology</topic><topic>Female</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Prospective Studies</topic><topic>Thyroid Nodule - diagnostic imaging</topic><topic>Thyroid Nodule - pathology</topic><topic>Thyroid Nodule - surgery</topic><topic>Tropical medicine</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BRAGA, Milena</creatorcontrib><creatorcontrib>CAVALCANTI, Teresa Cristina</creatorcontrib><creatorcontrib>MARTINS COLLACO, Luiz</creatorcontrib><creatorcontrib>GRAF, Hans</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The journal of clinical endocrinology and metabolism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BRAGA, Milena</au><au>CAVALCANTI, Teresa Cristina</au><au>MARTINS COLLACO, Luiz</au><au>GRAF, Hans</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of ultrasound-guided fine-needle aspiration biopsy in the diagnosis of complex thyroid nodules</atitle><jtitle>The journal of clinical endocrinology and metabolism</jtitle><addtitle>J Clin Endocrinol Metab</addtitle><date>2001-09-01</date><risdate>2001</risdate><volume>86</volume><issue>9</issue><spage>4089</spage><epage>4091</epage><pages>4089-4091</pages><issn>0021-972X</issn><eissn>1945-7197</eissn><coden>JCEMAZ</coden><abstract>Cystic thyroid nodules are considered to be one of the major causes of nondiagnostic and false-negative results on conventional fine-needle aspiration biopsy, thus limiting the potential of this method for the evaluation of complex (solid-cystic) thyroid nodules. Although ultrasound-guided fine-needle aspiration biopsy has emerged as a highly effective diagnostic method for the assessment of nonpalpable and difficult to palpate nodules, its role in complex nodules has not yet been carefully evaluated. In this study, we report the efficacy of ultrasound-guided fine-needle aspiration biopsy in 124 complex nodules in 113 patients. This method proved to be highly effective, yielding a satisfactory specimen for cytological evaluation in 94% of the nodules, suggesting that it is an excellent modality for the evaluation of complex nodules and also for the reevaluation of those nodules with a nondiagnostic result on conventional fine-needle aspiration biopsy.</abstract><cop>Bethesda, MD</cop><pub>Endocrine Society</pub><pmid>11549630</pmid><doi>10.1210/jc.86.9.4089</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Biological and medical sciences Biopsy, Needle - instrumentation Endocrinology Female Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prospective Studies Thyroid Nodule - diagnostic imaging Thyroid Nodule - pathology Thyroid Nodule - surgery Tropical medicine Ultrasonography |
title | Efficacy of ultrasound-guided fine-needle aspiration biopsy in the diagnosis of complex thyroid nodules |
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