Duration of the hemodynamic effects of N(G)-nitro-L-arginine methyl ester in vivo

The objective of this study was to quantify the duration of the hemodynamic activity of N(G)-nitro-l-arginine methyl ester (l-NAME) in a variety of different tissues following a single bolus injection of this nitric oxide synthase inhibitor to healthy rats. l-NAME (15 micromol x kg(-1)) was injected...

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Veröffentlicht in:	Nitric oxide 2000-04, Vol.4 (2), p.85-93
Hauptverfasser:	Conner, E M, Aiko, S, Fernandez, M, Battarbee, H D, Gray, L, Grisham, M B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Half-Life Hemodynamics - drug effects Injections, Intraperitoneal NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase Type III Rats Rats, Inbred Lew
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