pH-Dependent Spectral Properties of HpIX, TPPS2a, mTHPP and mTHPC

Lower extracellular pH in tumors as compared to normal tissues has been proposed to be a factor contributing to the tumor selective uptake of several photosensitizers. Therefore, the pH dependence of absorption and fluorescence spectral properties of four different drugs relevant for photodynamic th...

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Veröffentlicht in:	Photochemistry and photobiology 2001-08, Vol.74 (2), p.246-252
Hauptverfasser:	Čunderlíková, Beata, Bjørklund, Eva G., Pettersen, Erik O., Moan, Johan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Benzenesulfonates - chemistry Hematoporphyrins - chemistry Humans Hydrogen-Ion Concentration Mesoporphyrins - chemistry PHOTOCHEMISTRY, PHOTOPHYSICS AND PHOTOTECHNOLOGY Photochemotherapy Photosensitizing Agents - chemistry Porphyrins - chemistry Spectrometry, Fluorescence Spectrophotometry
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