Highly Regulated Expression of Subtilisin-like Proprotein Convertase PACE4 (SPC4) during Dentinogenesis

Expressions of mRNAs for four subtilisin-like proprotein convertases (SPCs: furin, PACE4, PC6, and PC8) and bone morphogenetic protein 4 (BMP4) in the rat molar tooth during development were analyzed by Northern blotting, reverse transcriptase-polymerase chain reaction (RT-PCR), and in situ hybridiz...

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Veröffentlicht in:	Biochemical and biophysical research communications 2000-06, Vol.272 (2), p.410-415
Hauptverfasser:	Akamatsu, Tetsuya, Matsuda, Yoshiko, Tsumura, Keiko, Tada, Jun, Parvin, Most.Nahid, Wei, Wei, Kanamori, Norio, Hosoi, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	ameloblast, odontoblast Animals Animals, Newborn BMP4 protein Bone Morphogenetic Protein 4 Bone Morphogenetic Proteins - genetics Dentin - cytology Dentin - embryology Dentin - enzymology Dentin - growth & development dentinogenesis Dentinogenesis - genetics Furin Gene Expression Regulation, Developmental Gene Expression Regulation, Enzymologic In Situ Hybridization Molar - cytology Molar - embryology Molar - enzymology Molar - growth & development molar tooth PACE4 PACE4 protein processing Proprotein Convertase 5 Proprotein Convertases Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Messenger - metabolism Serine Endopeptidases - genetics Serine Endopeptidases - metabolism subtilisin-like proprotein convertase Subtilisins - genetics
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