Bacterial comparative genomic hybridization: a method for directly identifying lateral gene transfer

Horizontally transferred DNA is largely responsible for the dissemination of virulence traits amongst bacteria. Rapid identification of acquired DNA remains difficult as whole-genome sequencing of outbreak strains is impractical, and microarray-based approaches, while powerful, are limited to genes...

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Veröffentlicht in:	Journal of molecular biology 2001-09, Vol.312 (1), p.1-5
Hauptverfasser:	Malloff, C A, Fernandez, R C, Lam, W L
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - genetics Deoxyribonucleases, Type II Site-Specific - genetics Deoxyribonucleases, Type II Site-Specific - metabolism DNA, Bacterial - chemistry Electrophoresis, Gel, Two-Dimensional Gene Transfer, Horizontal In Situ Hybridization - methods Pseudomonas aeruginosa Pseudomonas aeruginosa - genetics Restriction Mapping
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