Peritonitis induces rat cardiac myocytes to promote polymorphonuclear leukocyte emigration and activate endothelial cells: Effect of lipopolysaccharide pretreatment

OBJECTIVEPeritonitis induced by cecal ligation and perforation results in inflammation and dysfunction of the rat myocardium, an organ remote from the locus of infection. This peritonitis-induced pathology can be prevented by pretreating these animals with lipopolysaccharide before cecal ligation an...

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Veröffentlicht in:	Critical care medicine 2001-09, Vol.29 (9), p.1774-1779
Hauptverfasser:	Madorin, W Sean, Cepinskas, Gediminas, Kvietys, Peter R
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Cell Movement Emergency and intensive care: infection, septic shock Endothelium - metabolism Intensive care medicine Intercellular Adhesion Molecule-1 - pharmacology Ligation Lipopolysaccharides Male Medical sciences Muscle, Skeletal - metabolism Myocardium - metabolism Neutrophils - drug effects Oxidative Stress Peritonitis - etiology Peritonitis - metabolism Rats Rats, Sprague-Dawley Rats, Wistar
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