Design and Synthesis of [(2,3-Dichlorophenyl)piperazin-1-yl]alkylfluorenylcarboxamides as Novel Ligands Selective for the Dopamine D3 Receptor Subtype

The dopamine D3 receptor subtype has been recently targeted as a potential neurochemical modulator of the behavioral actions of psychomotor stimulants, such as cocaine. However, definitive behavioral investigations have been hampered by the lack of highly selective D3 agonists and antagonists. In an...

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Veröffentlicht in:Journal of medicinal chemistry 2001-09, Vol.44 (19), p.3175-3186
Hauptverfasser: Robarge, Michael J, Husbands, Stephen M, Kieltyka, Andrzej, Brodbeck, Robbin, Thurkauf, Andrew, Newman, Amy Hauck
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Sprache:eng
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